Porto Maphazardly - Representation of Place in Graphic Design

This project, Porto Maphazardly, examines the role of a graphic designer in exploring alternate means of mapping a location. A square in the Portuguese city of Porto was mapped through five sensory approaches: sound, smell, taste, activity, and color perception. The data that was gathered was translated into visuals to create a generated, but totally unique, graphic portrait of a place. The portmanteau maphazardly in the title combines the word ‘map’ with the adverb, ‘haphazardly,’ which means to do something determined by accident rather than design, without a clear plan or at the mercy of chance. The coining of the word is meant to evoke the extent to which the illustrations developed in response to observations, encounters and circumstance, rather than a client brief or a designer’s pre-decided aesthetic. In this report, the project is contextualized between the theory of critical cartography in the field of sociology, and the mapping works which already exist in the graphic design field, including the works of Paula Scher, Pedro Pina, Jeremy Wood, Alison Barnes and Kate McLean. The report presents a synthesized definition of ‘map’ for use in a visual, graphic analysis. A limited survey of the principles of information design is discussed, in its relation to traditional cartography, infographics, and our cognitive interpretations of maps. Finally, a brief analysis of changes in the nature of maps (smart-maps) is included, focusing on how user-centered maps have changed how one interacts with a city. The project endeavors to work in the realm of ‘designer as researcher,’ and is influenced by the writing of Russell Bestley and Ian Noble on visual research, in which the experiential nature of the data collection influences the design process. The methodology was developed through a series of test projects and by the application of ‘walking as method,’ and the report introduces the generative systems which were used to transform data— notes, photographs, and recordings—into illustrations. The final mappings are presented along with an analysis of successes and failures

The impact of artificial intelligence on the current and future practice of clinical cancer genomics.

Artificial intelligence (AI) is one of the most significant fields of development in the current digital age. Rapid advancements have raised speculation as to its potential benefits in a wide range of fields, with healthcare often at the forefront. However, amidst this optimism, apprehension and opposition continue to strongly persist. Oft-cited concerns include the threat of unemployment, harm to the doctor-patient relationship and questions of safety and accuracy. In this article, we review both the current and future medical applications of AI within the sub-speciality of cancer genomics

A study of time concepts found in primary reading materials

Thesis (Ed.M.)--Boston Universit

A study of time concepts found in primary reading materials

Thesis (Ed.M.)--Boston Universit

Problems in using social work records in assessing change

Thesis (M.S.)--Boston Universit

Discriminating nursery grounds of juvenile plaice (Pleuronectes platessa) in the south-eastern Irish Sea using otolith microchemistry

Nursery grounds are valuable habitats providing sources of food and refuge during early life stages for many commercially caught marine fish. Distinguishing between different nursery grounds and identifying habitat origin using trace elemental concentrations in aragonite structures of teleost fish has proved valuable in fish ecology and fisheries. This study aimed to (1) compare chemical signatures (elemental fingerprints) within sagittal otoliths of juvenile European plaice Pleuronectes platessa sampled from known nursery habitats in the south-eastern Irish Sea and (2) assess their potential and robustness as natural tags for identifying nursery grounds for the putative south-eastern Irish Sea plaice stock. Otoliths from juvenile plaice (‘1-group’, 6 to 15 cm total length) were obtained from 8 nursery grounds in coastal areas off north-west England and north Wales (including Anglesey) between June and August 2008. Solution-based inductively coupled plasma-mass spectrometry determined the concentrations of 10 elements (Li, Na, Mg, K, Mn, Zn, Rb, Sr, Sn, Ba), with significant differences in otolith element composition observed between all nursery grounds. Cross-validation linear discriminant function analysis (CV-LDFA) classified fish to their nursery ground of capture (46.2 to 93.3%), with a total group CV-LDFA accuracy of 71.0%. CV-LDFA between regions (north-west England and north Wales) classified fish with 82% accuracy. The discrimination of juvenile plaice from all 8 nursery grounds within the south-eastern Irish Sea using otolith microchemistry offers significant opportunities in the development of future effective fisheries management strategies through understanding the supply of juveniles from specific nursery grounds and adult plaice in the south-eastern Irish Sea

Modelling the dynamics of Plasmodium falciparum histidine-rich protein 2 in human malaria to better understand malaria rapid diagnostic test performance

Background: Effective diagnosis of malaria is a major component of case management. Rapid diagnostic tests (RDTs) based on Plasmodium falciparumhistidine-rich protein 2 (PfHRP2) are popular for diagnosis of this most virulent malaria infection. However, concerns have been raised about the longevity of the PfHRP2 antigenaemia following curative treatment in endemic regions. Methods. A model of PfHRP2 production and decay was developed to mimic the kinetics of PfHRP2 antigenaemia during infections. Data from two human infection studies was used to fit the model, and to investigate PfHRP2 kinetics. Four malaria RDTs were assessed in the laboratory to determine the minimum detectable concentration of PfHRP2. Results: Fitting of the PfHRP2 dynamics model indicated that in malaria nave hosts, P. falciparum parasites of the 3D7 strain produce 1.4 × 10 g of PfHRP2 per parasite per replication cycle. The four RDTs had minimum detection thresholds between 6.9 and 27.8 ng/mL. Combining these detection thresholds with the kinetics of PfHRP2, it is predicted that as few as 8 parasites/L may be required to maintain a positive RDT in a chronic infection. Conclusions: The results of the model indicate that good quality PfHRP2-based RDTs should be able to detect parasites on the first day of symptoms, and that the persistence of the antigen will cause the tests to remain positive for at least seven days after treatment. The duration of a positive test result following curative treatment is dependent on the duration and density of parasitaemia prior to treatment and the presence and affinity of anti-PfHRP2 antibodies

Development and validation of the Spirituality Instrument-27© (SpI-27©) in individuals with chronic illness

Aim: To develop and validate the Spirituality Instrument 27 (SpI-27©) in individuals with chronic illness (n = 249). Background: A need for a rigorously developed spirituality instrument that can be used with people who are religious and non-religious was identified. Methods: The initial 46-item instrument was developed from a concept analysis, a review of theoretical and empirical literature, and an appraisal of instruments measuring spirituality. Content validity was established with user focus groups and an expert panel review. A pilot study evaluated the online mode of administration and a descriptive correlational design assessed the reliability and validity of the instrument. Results: Results of exploratory factor analysis concluded a five-factor solution with 27 items: Connectedness with Others, Self-Transcendence, Self-Cognisance, Conservationism, and Connectedness with a Higher Power. Cronbach's alpha coefficients ranged from 0.823 to 0.911 for the five factors, and 0.904 for the overall scale. Paired t-tests, intra-class correlations, and weighted kappa values supported the temporal stability of the instrument. A significant and positive correlation was found between the SpI-27© and the Spirituality Index of Well-Being (p < 0.01), supporting convergent validity. Conclusions: Findings support the validity and reliability of the SpI-27©, which was developed with patient input and is underpinned by theoretical and empirical literature. The SpI-27© should be validated for use with other samples. The conceptual framework that guided the study can be used to enhance healthcare professionals' understanding of spirituality and its core dimensions